Action Mechanism of Malegra

 Sildenafil citrate is a component of Malegra 100mg formula. Phosphodiesterase type 5 enzyme, which is present in many bodily locations, including male genital regions like the penis and the prostate gland, is inhibited by sildenafil citrate.


The substance needed in the corpus cavernosum of the penis to cause an erection, cyclic guanosine monophosphate (cGMP), is broken down by the phosphodiesterase type 5 enzyme. Men who have PDE5 have sexual dysfunction because it reduces the amount of cGMP in their penile tissue. Ingesting sildenafil citrate inhibits this enzyme's ability to break down cGMP, which results in a buildup of the compound in the penis. Nitric oxide, which interacts with cGMP to relax the muscles of the corpus cavernosum, is consequently released when a person is sexually stimulated.


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