Mechanism of Action of Malegra

 Sildenafil citrate is an ingredient in Malegra 100mg. The Phosphodiesterase type 5 enzyme, which is present in many bodily locations, including the prostate gland and male genital regions like the penis, is inhibited by sildenafil citrate.


Cyclic Guanosine Monophosphate (cGMP), a substance required in the corpus cavernosum of the penis to cause an erection, is broken down by the phosphodiesterase type 5 enzyme. Because PDE5 reduces the amount of cGMP in penile tissue, it makes men's sexual function dysfunctional. When sildenafil citrate is consumed, it works against this enzyme to stop it from breaking down cGMP, resulting in a buildup of the substance in the penis. Nitric oxide is consequently released during sexual stimulation, and it interacts with cGMP to relax the muscles of the corpus cavernosum.


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